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This tool calculates the grey matter (GM, white matter (WM) and cerebrospinal fluid (CSF) segments from a brain MRI data set. The procedure has three parameters: Sampling rate determines the density of pixels considered in the calculation. Bias Regularisation serves for compensating modulations of the image intensity across the field-of-view. Depending on the degree of the artifact, a corresponding setting can be selected from the list. Cleanup is a procedure for rectifying the segmentation along the boundaries. It is recommended to use the default settings and only experiment with other parameter values if the segmentation fails. The default settings are available activating the default settings button 
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The results are the three segments WM, GM and CSF which are arranged as the frames in a "dynamic" series.