The rBV ( Autorad) model is intended for the quantitative assessment of the regional blood volume (rBV). The required measurements are a static C15O PET scan and external blood sampling. After a bolus inhalation of C15O inhalation an equilibration period should be allowed for 5 min. Then, blood data are sampled while a static PET acquisition is performed. The rBV can finally be calculated by dividing the PET activity by the integrated blood activity.