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Acquisition and Data Requirements
Image Data |
A static PET data set representing the average brain activity after injection of a H215O bolus. If a dynamic data set is loaded, the average pixel activity over the acquisition period will automatically be calculated during pixel-wise processing. The acquisition duration should only cover the uptake phase. |
Blood Data |
Blood activity sampled at a peripheral artery from the time of injection until the end of the PET acquisition. |
Blood Preprocessing
Because autoradiographic data is usually static, the 1-tissue compartment fit for estimating the delay and dispersion can not be applied. Therefore the only available blood preprocessing option is decay correction.
Note: The loaded blood data should have been corrected for delay and dispersion beforehand. This processing can be done on the Blood panel of in PKIN.
Model Preprocessing
ntab |
Number of pre-calculated values in the lookup table. Should be an even number. |
f |
Perfusion in [ml/min/100ml]. Please specify the range within which the tabulation is performed. |
p |
Partition coefficient or distribution volume of water in brain. This input parameter must be specified by the user. |
Map Parameters
f |
Regional perfusion in [ml/min/100ml]. It is calculated for each pixel by a table look-up procedure. Reasonable values are about 30 (white matter) and 60 (gray matter) ml/min/100ml [11] Note: The results are accurate only for voxels with the partition coefficient equal to that entered in the p-field. |